Publications of Andras Szilagyi

1. Szilagyi A, Zavodszky P (1995):
   Structural basis for the extreme thermostability of D-glyceraldehyde-3-phosphate dehydrogenase from Thermotoga maritima: analysis based on homology modelling.
   Protein Engineering, 8(8), 779-89.
   Impact factor: 3.605. Times cited: 32.
2. Magyar C, Szilagyi A, Zavodszky P (1996):
   Relationship between thermal stability and 3-D structure in a homology model of 3-isopropylmalate dehydrogenase from Escherichia coli.
   Protein Engineering, 9(8), 663-70.
   Impact factor: 1.975. Times cited: 11.
3. Wallon G, Lovett ST, Magyar C, Svingor A, Szilagyi A, Zavodszky P, Ringe D, Petsko GA (1997):
   Sequence and homology model of 3-isopropylmalate dehydrogenase from the psychrotrophic bacterium Vibrio sp. I5 suggest reasons for thermal instability.
   Protein Engineering, 10(6), 665-72.
   Impact factor: 1.631. Times cited: 43.
4. Nemeth A, Svingor A, Pocsik M, Dobo J, Magyar C, Szilagyi A, Gal P, Zavodszky P (2000):
   Mirror image mutations reveal the significance of an intersubunit ion cluster in the stability of 3-isopropylmalate dehydrogenase.
   FEBS Letters, 468(1), 48-52.
   Impact factor: 3.440. Times cited: 15.
5. Szilagyi A, Zavodszky P (2000):
   Structural differences between mesophilic, moderately thermophilic and extremely thermophilic protein subunits: results of a comprehensive survey.
   Structure with Folding & Design, 8(5), 493-504.
   Impact factor: 6.681. Times cited: 559.
6. Nemeth A, Kamondi Sz, Szilagyi A, Magyar C, Kovari Z, Zavodszky P (2002):
   Increasing the thermal stability of cellulase C using rules learned from thermophilic proteins: a pilot study.
   Biophysical Chemistry, 96(2-3), 229-41.
   Impact factor: 1.494. Times cited: 28.
7. Szilagyi A, Kovacs LK, Rakhely G, Zavodszky P (2002):
   Homology modelling reveals the structural background of the striking difference in thermal stability between two related [NiFe]hydrogenases.
   Journal of Molecular Modeling, 8(2), 58-64.
   Impact factor: 1.235. Times cited: 9.
8. Skolnick J, Zhang Y, Arakaki AK, Kolinski A, Boniecki M, Szilagyi A, Kihara D (2003):
   TOUCHSTONE: a unified approach to protein structure prediction.
   Proteins, 53(S6), 469-79.
   Impact factor: 4.313. Times cited: 62.
9. Tompa P, Buzder-Lantos P, Tantos A, Farkas A, Szilagyi A, Banoczi Z, Hudecz F, Friedrich P (2004):
   On the sequential determinants of calpain cleavage.
   Journal of Biological Chemistry, 279(20), 20775-85.
   Impact factor: 6.355. Times cited: 263.
10. Szilagyi A, Grimm V, Arakaki AK, Skolnick J (2005):
    Prediction of physical protein-protein interactions.
    Physical Biology, 2(2), S1-16.
    Impact factor: 2.773. Times cited: 77.
11. Szilagyi A, Skolnick J (2006):
    Efficient prediction of nucleic acid binding function from low-resolution protein structures.
    Journal of Molecular Biology, 358(3), 922-33.
    Impact factor: 4.890. Times cited: 125.
12. Szilagyi A, Kardos J, Osvath Sz, Barna L, Zavodszky P (2007):
    Protein folding.
    In: Lajtha A, Banik N (eds.): Handbook of Neurochemistry and Molecular Neurobiology, Volume 7, Chapter 10. pp. 303-344. Springer, 2007
    
13. Graczer E, Varga A, Hajdu I, Melnik B, Szilagyi A, Semisotnov G, Zavodszky P, Vas M (2007):
    Rates of unfolding, rather than refolding, determine thermal stabilities of thermophilic, mesophilic and psychrotrophic IPMDHs.
    Biochemistry, 46(41), 11536-49.
    Impact factor: 3.368. Times cited: 16.
14. Szilagyi A (2008):
    A mathematically related singularity and the maximum size of protein domains.
    Proteins, 71(4), 2086-8.
    Impact factor: 3.419. Times cited: 1.
15. Szilagyi A, Gyorffy D, Zavodszky P (2008):
    The twilight zone between protein order and disorder.
    Biophysical Journal, 95(4), 1612-26.
    Impact factor: 4.683. Times cited: 25.
16. Hajdu I, Bothe C, Szilagyi A, Kardos J, Gal P, Zavodszky P (2008):
    Adjustment of conformational flexibility of glyceraldehyde-3-phosphate dehydrogenase as a means of thermal adaptation and allosteric regulation.
    European Biophysical Journal, 37(7), 1139-44.
    Impact factor: 2.409. Times cited: 6.
17. Kamondi S, Szilagyi A, Barna L, Zavodszky P (2008):
    Engineering the thermostability of a TIM-barrel enzyme by rational family shuffling.
    Biochemical and Biophysical Research Communications, 374(4), 725-40.
    Impact factor: 2.648. Times cited: 15.
18. Nimrod G, Szilagyi A, Leslie C, Ben-Tal N (2009):
    Identification of DNA-binding proteins using structural, electrostatic and evolutionary features.
    Journal of Molecular Biology, 387(4), 1040-53.
    Impact factor: 3.871. Times cited: 65.
19. Hajdu I, Szilagyi A, Kardos J, Zavodszky P (2009):
    A link between hinge-bending domain motions and the temperature dependence of catalysis in IPMDH.
    Biophysical Journal, 96(12), 5003-12.
    Impact factor: 4.390. Times cited: 12.
20. Than NG, Romero R, Goodman M, Weckle A, Xing J, Dong Z, Xu Y, Tarquini F, Szilagyi A, Gal P, Hou Z, Tarca AL, Kim CJ, Kim JS, Haidarian S, Uddin M, Bohn H, Benirschke K, Santolaya-Forgas J, Grossman LI, Erez O, Hassan SS, Zavodszky P, Papp Z, Wildman DE (2009):
    A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death.
    Proceedings of the National Academy of Sciences USA, 106(24), 9731-6.
    Impact factor: 9.432. Times cited: 161.
21. Kucukural A, Szilagyi A, Sezerman O, Zhang Y (2010):
    Protein homology analysis for function prediction with parallel sub-graph isomorphism.
    In: Lodhi H, Yamanishi Y (eds.): Chemoinformatics and advanced machine learning perspectives: complex computational methods and collaborative perspectives. IGI Global, 2010, pp. 129-144.
    
22. Mukherjee S, Szilagyi A, Roy A, Zhang Y (2010):
    Genome-wide protein structure prediction.
    In: Kolinski A (ed.): Multiscale approaches to protein modeling: structure prediction, dynamics, thermodynamics and macromolecular assemblies. Springer 2010, pp. 255-280.
    
23. Nimrod G, Schushan M, Szilagyi A, Leslie C, Ben-Tal N (2010):
    iDBPs: A web server for the identification of DNA binding proteins.
    Bioinformatics, 26(5), 692-3.
    Impact factor: 4.877. Times cited: 62.
24. Wu S, Szilagyi A, Yang Zhang (2011):
    Improving protein structure prediction using multiple sequence-based contact predictions.
    Structure, 19(8), 1182-91.
    Impact factor: 6.347. Times cited: 56.
25. Than G, Romero R, Meiri H, Erez O, Xu Y, Tarquini F, Barna L, Szilagyi A, Ackerman R, Sammar M, Fule T, Karaszi K, Kovalszky I, Dong Z, Kim CJ, Zavodszky P, Papp Z, Gonen R (2011):
    PP13, maternal ABO blood groups and the risk assessment of pregnancy complications
    PLoS ONE, 6(7), e21564.
    Impact factor: 4.092. Times cited: 40.
26. Szilagyi A, Zhang Y, Zavodszky P (2012):
    Intra-chain 3D segment swapping spawns the evolution of new multidomain protein architectures.
    Journal of Molecular Biology, 415(1), 221-35.
    Impact factor: 3.905. Times cited: 13.
27. Gyorffy D, Zavodszky P, Szilagyi A (2012):
    "Pull moves" for rectangular lattice polymers are not fully reversible.
    IEEE/ACM Transactions on Computational Biology and Bioinformatics, 9(6), 1847-9.
    Impact factor: 1.616. Times cited: 5.
28. Abrusan G, Szilagyi A, Zhang Y, Papp B (2013):
    Turning gold into 'junk': transposable elements utilize central proteins of cellular networks.
    Nucleic Acids Research, 41(5), 3190-200.
    Impact factor: 8.808. Times cited: 14.
29. Csermely P, Nussinov R, Szilagyi A (2013):
    From allosteric drugs to allo-network drugs: State of the art and trends of design, synthesis, and computational methods.
    Current Topics in Medicinal Chemistry, 13(1), 2-4.
    Impact factor: 3.453. Times cited: 22.
30. Szilagyi A, Nussinov R, Csermely P (2013):
    Allo-network drugs: Extension of the allosteric drug concept to protein-protein interaction and signaling networks.
    Current Topics in Medicinal Chemistry, 13(1), 64-77.
    Impact factor: 3.453. Times cited: 59.
31. Abrusan G, Zhang Y, Szilagyi A (2013):
    Structure prediction and analysis of DNA transposon and LINE retrotransposon proteins.
    Journal of Biological Chemistry, 288(22), 16127-38.
    Impact factor: 4.600. Times cited: 8.
32. Kucukural A, Szilagyi A, Sezerman O, Zhang Y (2013):
    Protein homology analysis for function prediction with parallel sub-graph isomorphism.
    In: Bioinformatics: Concepts, Methodologies, Tools, and Applications. IGI Global, 2013, pp. 386-399.
    
33. Szilagyi A, Zhang Y (2014):
    Template-based structure modeling of protein-protein interactions.
    Current Opinion in Structural Biology, 24(Feb), 10-23.
    Impact factor: 7.201. Times cited: 110.
34. Than NG, Balogh A, Romero R, Karpati E, Erez O, Szilagyi A, Kovalszky I, Sammar M, Gizurarson S, Matko J, Zavodszky P, Papp Z, Meiri H (2014):
    Placental Protein 13 (PP13) - A placental immunoregulatory galectin protecting pregnancy.
    Frontiers in Immunology, 5, 348.
    Impact factor: 5.695. Times cited: 79.
35. Graczer E, Bacso A, Konya D, Kazi A, Soos T, Molnar L, Szimler T, Beinrohr L, Szilagyi A, Zavodszky P, Vas M (2014):
    Drugs against Mycobacterium tuberculosis 3-isopropylmalate dehydrogenase can be developed using homologous enzymes as surrogate targets
    Protein & Peptide Letters, 21(12), 1295-307.
    Impact factor: 1.068. Times cited: 2.
36. Abrusan G, Yant SR, Szilagyi A, Marsh JA, Mates L, Izsvak Zs, Barabas O, Ivics Z (2016):
    Structural determinants of Sleeping Beauty transposase activity
    Molecular Therapy, 24(8), 1369-77.
    Impact factor: 6.688. Times cited: 7.
37. Szilagyi A, Gyorffy D, Zavodszky P (2017):
    Segment swapping aided the evolution of enzyme function: The case of uroporphyrinogen III synthase.
    Proteins: Structure, Function, and Bioinformatics, 85(1), 46-53.
    Impact factor: 2.289. Times cited: 3.
38. Gyimesi G, Zavodszky P, Szilagyi A (2017):
    Calculation of configurational entropy differences from conformational ensembles using Gaussian mixtures
    Journal of Chemical Theory and Computation, 13(1), 29-41.
    Impact factor: 5.245. Times cited: 16.
39. Oroszlán G, Dani R, Szilágyi A, Závodszky P, Thiel S, Gál P, Dobó J (2017):
    Extensive basal level activation of complement mannose-binding lectin-associated serine protease-3: kinetic modeling of lectin pathway activation provides possible mechanism
    Frontiers in Immunology, 8, 1821.
    Impact factor: 6.429. Times cited: 16.
40. Balogh A, Kárpáti É, Schneider AE, Hetey S, Szilágyi A, Juhász K, László G, Hupuczi P, Závodszky P, Papp Z, Matkó J, Than NG (2019):
    Sex hormone-binding globulin provides a novel entry pathway for estradiol and influences subsequent signaling in lymphocytes via membrane receptor
    Scientific Reports, 9(1), 4.
    Impact factor: 4.011. Times cited: 14.
41. Szimler T, Gráczer É, Györffy D, Végh B, Szilágyi A, Hajdú I, Závodszky P, Vas M (2019):
    New type of interaction between the SARAH domain of the tumour suppressor RASSF1A and its mitotic kinase Aurora A
    Scientific Reports, 9(1), 5550.
    Impact factor: 4.011. Times cited: 4.
42. King JR, Wilson ML, Hetey S, Kiraly P, Matsuo K, Castaneda AV, Toth E, Krenacs T, Hupuczi P, Mhawech-Fauceglia P, Balogh A, Szilagyi A, Matko J, Papp Z, Roman LD, Cortessis VK, Than NG (2019):
    Dysregulation of placental functions and immune pathways in complete hydatidiform moles
    International Journal of Molecular Sciences, 20(20), 4999.
    Impact factor: 4.556. Times cited: 12.
43. Szilagyi A, Gelencser Z, Romero R, Xu Y, Kiraly P, Demeter A, Palhalmi J, Gyorffy BA, Juhasz K, Hupuczi P, Kekesi KA, Meinhardt G, Papp Z, Draghici S, Erez O, Tarca AL, Knöfler M, Than NG (2020):
    Placenta-specific genes, their regulation during villous trophoblast differentiation and dysregulation in preterm preeclampsia
    International Journal of Molecular Sciences, 21(2), 628.
    Impact factor: 5.924. Times cited: 24.
44. Meinhardt G, Haider S, Kunihs V, Saleh L, Pollheimer J, Fiala C, Hetey S, Feher Z, Szilagyi A, Than NG, Knöfler M (2020):
    Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta
    Proceedings of the National Academy of Sciences USA, 117(24), 13562-13570.
    Impact factor: 11.205. Times cited: 68.
45. Szabo S, Karaszi K, Romero R, Toth E, Szilagyi A, Gelencser Z, Xu Y, Balogh A, Szalai G, Hupuczi P, Hargitai B, Krenacs T, Hunyadi-Gulyas E, Darula Z, Kekesi KA, Tarca AL, Erez O, Juhasz G, Kovalszky I, Papp Z, Than NG (2020):
    Proteomic identification of Placental Protein 1 (PP1), PP8, and PP22 and characterization of their placental expression in healthy pregnancies and in preeclampsia.
    Placenta, 99( ), 197-207.
    Impact factor: 3.481. Times cited: 2.
46. Balogh A, Reiniger L, Hetey S, Kiraly P, Toth E, Karaszi K, Juhasz K, Gelencser Z, Zvara A, Szilagyi A, Puskas LG, Matko J, Papp Z, Kovalszky I, Juhasz C, Than NG. (2020):
    Decreased expression of ZNF554 in gliomas is associated with the activation of tumor pathways and shorter patient survival
    Int J Mol Sci., 21(16), 5762.
    Impact factor: 5.924. Times cited: 5.
47. Hajdú I, Szilágyi A, Végh BM, Wacha A, Györffy D, Gráczer É, Somogyi M, Gál P, Závodszky P (2020):
    Ligand-induced conformational rearrangements regulate the switch between membrane-proximal and distal functions of Rho kinase 2
    Commun Biol., 3(1), 721.
    Impact factor: 6.268. Times cited: 3.
48. Tarca AL, Pataki BA, Romero R, Sirota M, Guan Y, Kutum R, Gomez-Lopez N, Done B, Bhatti G, Yu T, Andreoletti G, Chaiworapongsa T, The DREAM Preterm Birth Prediction Challenge Consortium, Hassan SS, Hsu CD, Aghaeepour N, Stolovitzky G, Csabai I, Costello JC (2021):
    Crowdsourcing assessment of maternal blood multi-omics for predicting gestational age and preterm birth
    Cell Reports Medicine, 2(6), 100323.
    Times cited: 32.
49. Szabolcsi Z, Demeter A, Kiraly P, Balogh A, Wilson ML, King JR, Hetey S, Gelencser Z, Matsuo K, Hargitai B, Mhawech-Fauceglia P, Hupuczi P, Szilagyi A, Papp Z, Roman LD, Cortessis VK, Than NG (2021):
    Epigenetic dysregulation of trophoblastic gene expression in gestational trophoblastic disease
    Biomedicines, 9(12), 1935.
    Impact factor: 6.081. Times cited: 4.
50. Than NG, Posta M, Györffy D, Orosz L, Orosz G, Rossi SW, Ambrus-Aikelin G, Szilágyi A, Nagy S, Hupuczi P, Török O, Tarca AL, Offer E, Papp Z, Romero R (2022):
    A praeeclampsia korai betegségútvonalai, biomarkerei és négy különböző molekuláris alosztálya
    Nőgyógyászati és Szülészeti Továbbképző Szemle, XXIV(1), 6-16.
    Times cited: 0.
51. Than NG, Posta M, Györffy D, Orosz L, Orosz G, Rossi SW, Ambrus-Aikelin G, Szilágyi A, Nagy S, Hupuczi P, Török O, Tarca AL, Erez O, Papp Z, Romero R (2022):
    Early pathways, biomarkers and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological and high dimensional biology studies
    Placenta, 125, 10-19.
    Impact factor: 3.8. Times cited: 13.
52. Than NG, Romero R, Györffy D, Posta M, Bhatti G, Done B, Chaemsaithong P, Jung E, Suksai M, Gotsch F, Gallo DM, Bosco M, Kim B, Kim YM, Chaiworapongsa T, Rossi SW, Szilágyi A, Erez O, Tarca AL, Papp Z (2023):
    Molecular subclasses of preeclampsia characterized by a longitudinal maternal proteomics study: distinct biomarkers, disease pathways and options for prevention
    Journal of Perinatal Medicine, 51(1), 51-68.
    Impact factor: 2.4. Times cited: 5.
53. Hajdú I, Végh BM, Szilágyi A, Závodszky P (2023):
    Beta-secretase 1 recruits amyloid-beta precursor protein to ROCK2 kinase, resulting in erroneous phosphorylation and beta-amyloid plaque formation
    International Journal of Molecular Sciences, 24(13), 10416.
    Impact factor: 5.6. Times cited: 0.
54. Than NG, Romero R, Posta M, Györffy D, Szalai G, Rossi SW, Szilágyi A, Hupuczi P, Nagy S, Török O, Tarca AL, Erez O, Ács N, Papp Z (2023):
    Classification of preeclampsia according to molecular clusters with the goal of achieving personalized prevention
    Journal of Reproductive Immunology, 161, 104172.
    Impact factor: 3.4. Times cited: 0.
55. Györffy D, Závodszky P, Szilágyi A (2023):
    A kinetic transition network model reveals the diversity of protein dimer formation mechanisms
    Biomolecules, 13(12), 1708.
    Impact factor: 5.5. Times cited: 0.
56. Toth E, Gyorffy D, Posta M, Hupuczi P, Balogh A, Szalai G, Orosz G, Orosz L, Szilagyi A, Oravecz O, Veress L, Nagy S, Torok O, Murthi P, Erez O, Papp Z, Acs N, Than NG (2024):
    Decreased Expression of Placental Proteins in Recurrent Pregnancy Loss: Functional Relevance and Diagnostic Value
    International Journal of Molecular Sciences, 25(3), 1865.
    Impact factor: 5.6. Times cited: 0.

Total impact factor: 226.139
Total citations: 2223 (2184 without self-citations)
h-index = 21

Per-article citation numbers last updated on Dec 21, 2023. Total citation numbers updated on Dec 21, 2023.